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Involvement of reactive oxygen species in cyclic stretch-induced NF-κB activation in human fibroblast cells
1. Uniaxial cyclic stretch leads to an upregulation of cyclooxygenase (COX)-2 through increases in the intracellular Ca(2+) concentration via the stretch-activated (SA) channel and following nuclear factor kappa B (NF-κB) activation in human fibroblasts. However, the signaling mechanism as to how th...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1576145/ https://ncbi.nlm.nih.gov/pubmed/15778740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706182 |
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