Evidence that reactive oxygen species do not mediate NF-κB activation

It has been postulated that reactive oxygen species (ROS) may act as second messengers leading to nuclear factor (NF)-κB activation. This hypothesis is mainly based on the findings that N-acetyl-l-cysteine (NAC) and pyrrolidine dithiocarbamate (PDTC), compounds recognized as potential antioxidants,...

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Bibliographic Details
Main Authors: Hayakawa, Makio, Miyashita, Hiroshi, Sakamoto, Isao, Kitagawa, Masatoshi, Tanaka, Hirofumi, Yasuda, Hideyo, Karin, Michael, Kikugawa, Kiyomi
Format: Artigo
Language:Inglês
Published: Oxford University Press 2003
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC165656/
https://ncbi.nlm.nih.gov/pubmed/12839997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg332
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