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Optimization of the Secondary Drying Step in Freeze Drying Using TDLAS Technology

The secondary drying phase in freeze drying is mostly developed on a trial-and-error basis due to the lack of appropriate noninvasive process analyzers. This study describes for the first time the application of Tunable Diode Laser Absorption Spectroscopy, a spectroscopic and noninvasive sensor for...

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Autori principali: Schneid, Stefan C., Gieseler, Henning, Kessler, William J., Luthra, Suman A., Pikal, Michael J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066362/
https://ncbi.nlm.nih.gov/pubmed/21359604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-011-9600-7
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