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Optical coherence tomography-based freeze-drying microscopy

A new type of freeze-drying microscope based upon time-domain optical coherence tomography is presented here (OCT-FDM). The microscope allows for real-time, in situ 3D imaging of pharmaceutical formulations in vials relevant for manufacturing processes with a lateral resolution of <7 μm and an ax...

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Detalhes bibliográficos
Main Authors: Mujat, Mircea, Greco, Kristyn, Galbally-Kinney, Kristin L., Hammer, Daniel X., Ferguson, R. Daniel, Iftimia, Nicusor, Mulhall, Phillip, Sharma, Puneet, Pikal, Michael J., Kessler, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: Optical Society of America 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255342/
https://ncbi.nlm.nih.gov/pubmed/22254168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.3.000055
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