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NIR Spectroscopy Applications in the Development of a Compacted Multiparticulate System for Modified Release

The purpose of this study was to utilize near-infrared spectroscopy and chemical imaging to characterize extrusion-spheronized drug beads, lipid-based placebo beads, and modified release tablets prepared from blends of these beads. The tablet drug load (10.5–19.5 mg) of theophylline (2.25 mg increme...

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Hlavní autoři: Cantor, Stuart L., Hoag, Stephen W., Ellison, Christopher D., Khan, Mansoor A., Lyon, Robbe C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066347/
https://ncbi.nlm.nih.gov/pubmed/21240575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9580-z
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