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Development and Evaluation of a Floating Multiparticulate Gastroretentive System for Modified Release of AZT

The aim of this study was to develop and evaluate a floating multiparticulate gastroretentive system for the modified release of zidovudine (AZT). AZT was used as a model drug water-soluble at therapeutic doses. The floating gastroretentive system was obtained by co-precipitation, after solvent diff...

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Detalhes bibliográficos
Main Authors: Yoshida, Valquíria Miwa Hanai, de Oliveira Junior, José Martins, Gonçalves, Marcos Moisés, Vila, Marta Maria Duarte Carvalho, Chaud, Marco Vinícius
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134651/
https://ncbi.nlm.nih.gov/pubmed/21562720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-011-9627-9
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