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Stability of adriamycin-induced DNA adducts and interstrand crosslinks.

The stability of adriamycin-induced DNA adducts and interstrand crosslinks was measured at 37 degrees C by three independent procedures. The loss of [14C]-labelled adducts was described by two first-order decays with half-lives of 7.4 h (60% amplitude) and 39 h (40%). The loss of the drug chromophor...

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Udgivet i:Nucleic Acids Res
Principais autores: van Rosmalen, A, Cullinane, C, Cutts, S M, Phillips, D R
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306628/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7870589/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.1.42
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