A Humanized Mouse Model to Study Hepatitis C Virus Infection, Immune Response, and Liver Disease

BACKGROUND & AIMS: Studies of hepatitis C virus (HCV) infection, immunopathogenesis, and resulting liver diseases have been hampered by the lack of a small animal model. We developed humanized mice with human immune system and liver tissues to improve the studies of hepatitis C pathogenesis and...

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Detalhes bibliográficos
Main Authors: Washburn, Michael L., Bility, Moses T., Zhang, Liguo, Kovalev, Grigoriy I., Buntzman, Adam, Frelinger, Jeffery A., Barry, Walter, Ploss, Alexander, Rice, Charles M., Su, Lishan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066273/
https://ncbi.nlm.nih.gov/pubmed/21237170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.01.001
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