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HIV-1 infection and pathogenesis in a novel humanized mouse model
The Rag2-γC double-knockout (DKO) mouse lacks T, B, and natural killer (NK) cells, and allows development of a functional human immune system with human CD34(+) hematopoietic stem/progenitor cells (DKO-hu HSCs). Normal human T, B, and dendritic cells are present in peripheral blood, thymus, spleen,...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852218/ https://ncbi.nlm.nih.gov/pubmed/17132723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-07-033159 |
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