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An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids
Hepatic hydroxylation is an essential step in the metabolism and excretion of bile acids and is necessary to avoid pathologic conditions such as cholestasis and liver damage. In this report, we demonstrate that the human xenobiotic receptor SXR (steroid and xenobiotic receptor) and its rodent homolo...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC30661/ https://ncbi.nlm.nih.gov/pubmed/11248086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051014398 |
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