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Role of IL-2 secreted by PADRE-specific CD4(+) T cells in enhancing E7-specific CD8(+) T-cell immune responses

CD4(+) T helper cells are known to play an integral role in the generation of CD8(+) T-cell immune responses. We have previously shown that co-administration of DNA vaccines containing E6 or E7 protein of human papillomavirus 16 (HPV-16) combined with DNA encoding invariant (Ii) chain in which class...

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Détails bibliographiques
Auteurs principaux: Kim, D, Monie, A, He, L, Tsai, Y-C, Hung, C-F, Wu, T-C
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066096/
https://ncbi.nlm.nih.gov/pubmed/18273057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.gt.3303102
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