Recovery from Cyclophosphamide-Induced Lymphopenia Results in Expansion of Immature Dendritic Cells Which Can Mediate Enhanced Prime-Boost Vaccination Antitumor Responses In Vivo When Stimulated with the TLR3 Agonist Poly(I:C)

Recent preclinical studies suggest that vaccination following adoptive transfer of CD8(+) T cells into a lymphopenic host can augment the therapeutic antitumor responses of the transferred cells. However, the mechanism by which the lymphopenic microenvironment benefits Ag-specific CD8(+) T cell resp...

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Detalhes bibliográficos
Main Authors: Salem, Mohamed L., Díaz-Montero, C. Marcela, Al-Khami, Amir A., El-Naggar, Sabry A., Naga, Osama, Montero, Alberto J., Khafagy, Ahmed, Cole, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066095/
https://ncbi.nlm.nih.gov/pubmed/19201856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0801829
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