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Cyclophosphamide Induces Dynamic Alterations in the Host Microenvironments Resulting in a Flt3 Ligand-Dependent Expansion of Dendritic Cells

Preconditioning a recipient host with lymphodepletion can markedly augment adoptive T cell therapy. However, the precise mechanisms involved are poorly understood. In a recent study, we observed a significant increase in the circulating levels of dendritic cells (DCs; CD11c(+)CD11b(+)) during the re...

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Detalhes bibliográficos
Main Authors: Salem, Mohamed L., AL-Khami, Amir A., EL-Naggar, Sabry A., Díaz-Montero, C. Marcela, Chen, Yian, Cole, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066076/
https://ncbi.nlm.nih.gov/pubmed/20083664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902309
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