Selective stimulation of translation of leaderless mRNA by initiation factor 2: evolutionary implications for translation
Translation initiation in bacteria involves a stochastic binding mechanism in which the 30S ribosomal subunit first binds either to mRNA or to initiator tRNA, fMet-tRNA(f)(Met). Leaderless λ cI mRNA did not form a binary complex with 30S ribosomes, which argues against the view that ribosomal recrui...
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| Gepubliceerd in: | EMBO J |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2000
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306601/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10921890/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.15.4101 |
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