Selective stimulation of translation of leaderless mRNA by initiation factor 2: evolutionary implications for translation

Translation initiation in bacteria involves a stochastic binding mechanism in which the 30S ribosomal subunit first binds either to mRNA or to initiator tRNA, fMet-tRNA(f)(Met). Leaderless λ cI mRNA did not form a binary complex with 30S ribosomes, which argues against the view that ribosomal recrui...

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Pubblicato in:	EMBO J
Autori principali:	Grill, Sonja, Gualerzi, Claudio O., Londei, Paola, Bläsi, Udo
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2000
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306601/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10921890/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.15.4101
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