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Selective stimulation of translation of leaderless mRNA by initiation factor 2: evolutionary implications for translation
Translation initiation in bacteria involves a stochastic binding mechanism in which the 30S ribosomal subunit first binds either to mRNA or to initiator tRNA, fMet-tRNA(f)(Met). Leaderless λ cI mRNA did not form a binary complex with 30S ribosomes, which argues against the view that ribosomal recrui...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2000
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC306601/ https://ncbi.nlm.nih.gov/pubmed/10921890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.15.4101 |
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