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A new clustering of antibody CDR loop conformations

Previous analyses of the complementarity determining regions (CDRs) of antibodies have focused on a small number of “canonical” conformations for each loop. This is primarily the result of the work of Chothia and colleagues, most recently in 1997. Because of the widespread utility of antibodies, we...

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Detalhes bibliográficos
Main Authors: North, Benjamin, Lehmann, Andreas, Dunbrack, Roland L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065967/
https://ncbi.nlm.nih.gov/pubmed/21035459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.10.030
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