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Elongation arrest is a physiologically important function of signal recognition particle

Signal recognition particle (SRP) targets proteins for co-translational insertion through or into the endoplasmic reticulum membrane. Mammalian SRP slows nascent chain elongation by the ribosome during targeting in vitro. This ‘elongation arrest’ activity requires the SRP9/14 subunit of the particle...

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Bibliografiska uppgifter
Huvudupphovsmän: Mason, Nicola, Ciufo, Leonora F., Brown, Jeremy D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2000
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC306590/
https://ncbi.nlm.nih.gov/pubmed/10921896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.15.4164
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