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Signal recognition particle mediates a transient elongation arrest of preprolactin in reticulocyte lysate

Signal recognition particle (SRP) is a ribonucleoprotein that functions in the targeting of ribosomes synthesizing presecretory proteins to the ER. SRP binds to the signal sequence as it emerges from the ribosome, and in wheat germ extracts, arrests further elongation. The translation arrest is rele...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1989
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2115964/
https://ncbi.nlm.nih.gov/pubmed/2556403
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