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Elongation arrest is a physiologically important function of signal recognition particle
Signal recognition particle (SRP) targets proteins for co-translational insertion through or into the endoplasmic reticulum membrane. Mammalian SRP slows nascent chain elongation by the ribosome during targeting in vitro. This ‘elongation arrest’ activity requires the SRP9/14 subunit of the particle...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC306590/ https://ncbi.nlm.nih.gov/pubmed/10921896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.15.4164 |
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