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Biosynthesis of Selenocysteine, the 21st Amino Acid in the Genetic Code, and a Novel Pathway for Cysteine Biosynthesis

The biosynthetic pathway for selenocysteine (Sec), the 21st amino acid in the genetic code whose codeword is UGA, was recently determined in eukaryotes and archaea. Sec tRNA, designated tRNA([Ser]Sec), is initially aminoacylated with serine by seryl-tRNA synthetase and the resulting seryl moiety is...

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Autori principali: Turanov, Anton A., Xu, Xue-Ming, Carlson, Bradley A., Yoo, Min-Hyuk, Gladyshev, Vadim N., Hatfield, Dolph L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Nutrition 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065758/
https://ncbi.nlm.nih.gov/pubmed/22332041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/an.110.000265
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