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Evaluating sequence-derived mtDNA length heteroplasmy by amplicon size analysis

Length heteroplasmy (LH) in mitochondrial (mt)DNA is usually observed in homopolymeric tracts and manifest as mixture of various length variants. The generally used difference-coded annotation to report mtDNA haplotypes does not express the degree of LH variation present in a sample, even more so, i...

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Detalhes bibliográficos
Main Authors: Berger, C., Hatzer-Grubwieser, P., Hohoff, C., Parson, W.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064993/
https://ncbi.nlm.nih.gov/pubmed/21067985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fsigen.2010.10.002
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