Chromatin and DNA methylation dynamics during retinoic acid-induced RET gene transcriptional activation in neuroblastoma cells

Although it is well known that RET gene is strongly activated by retinoic acid (RA) in neuroblastoma cells, the mechanisms underlying such activation are still poorly understood. Here we show that a complex series of molecular events, that include modifications of both chromatin and DNA methylation...

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Autors principals: Angrisano, T., Sacchetti, S., Natale, F., Cerrato, A., Pero, R., Keller, S., Peluso, S., Perillo, B., Avvedimento, V. E., Fusco, A., Bruni, C. B., Lembo, F., Santoro, M., Chiariotti, L.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
Matèries:
Gene Regulation, Chromatin and Epigenetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064803/
https://ncbi.nlm.nih.gov/pubmed/20952403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq864
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