7SK small nuclear RNA directly affects HMGA1 function in transcription regulation

Non-coding (nc) RNAs are increasingly recognized to play important regulatory roles in eukaryotic gene expression. The highly abundant and essential 7SK ncRNA has been shown to negatively regulate RNA Polymerase II transcription by inactivating the positive transcription elongation factor b (P-TEFb)...

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Main Authors: Eilebrecht, Sebastian, Brysbaert, Guillaume, Wegert, Thomas, Urlaub, Henning, Benecke, Bernd-Joachim, Benecke, Arndt
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2011
Assuntos:
Gene Regulation, Chromatin and Epigenetics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064786/
https://ncbi.nlm.nih.gov/pubmed/21087998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1153
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