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Concentration-dependent exchange accelerates turnover of proteins bound to double-stranded DNA

The multistep kinetics through which DNA-binding proteins bind their targets are heavily studied, but relatively little attention has been paid to proteins leaving the double helix. Using single-DNA stretching and fluorescence detection, we find that sequence-neutral DNA-binding proteins Fis, HU and...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Graham, John S., Johnson, Reid C., Marko, John F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064784/
https://ncbi.nlm.nih.gov/pubmed/21097894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1140
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