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Hypermethylation of human DNA sequences in embryonal carcinoma cells and somatic tissues but not in sperm.
Certain human DNA sequences are much less methylated at CpG sites in sperm than in various adult somatic tissues. The DNA of term placenta displays intermediate levels of methylation at these sequences (Sp-0.3 sequences). We report here that pluripotent embryonal carcinoma (EC) cells derived from te...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1987
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC306478/ https://ncbi.nlm.nih.gov/pubmed/2825135 |
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