Hypermethylation of ribosomal DNA in human breast carcinoma

We examined the methylation status of the transcribed domain of ribosomal DNA (rDNA) in 58 patients with breast cancer. The mean percent of methylation was significantly higher in breast tumours than that of normal control samples (P< 0.0001). This increased rDNA methylation was associated with o...

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Bibliographic Details
Main Authors: Yan, P S, Rodriguez, F J, Laux, D E, Perry, M R, Standiford, S B, Huang, T H-M
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2000
Subjects:
Regular Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363317/
https://ncbi.nlm.nih.gov/pubmed/10682657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.0955
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