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Hypermethylation of ribosomal DNA in human breast carcinoma

We examined the methylation status of the transcribed domain of ribosomal DNA (rDNA) in 58 patients with breast cancer. The mean percent of methylation was significantly higher in breast tumours than that of normal control samples (P< 0.0001). This increased rDNA methylation was associated with o...

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Detalhes bibliográficos
Main Authors: Yan, P S, Rodriguez, F J, Laux, D E, Perry, M R, Standiford, S B, Huang, T H-M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363317/
https://ncbi.nlm.nih.gov/pubmed/10682657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.0955
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