Comparative whole genome DNA methylation profiling of cattle sperm and somatic tissues reveals striking hypomethylated patterns in sperm

BACKGROUND: Although sperm DNA methylation has been studied in humans and other species, its status in cattle is largely unknown. RESULTS: Using whole-genome bisulfite sequencing (WGBS), we profiled the DNA methylome of cattle sperm through comparison with three somatic tissues (mammary gland, brain...

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Dades bibliogràfiques
Publicat a:Gigascience
Autors principals: Zhou, Yang, Connor, Erin E, Bickhart, Derek M, Li, Congjun, Baldwin, Ransom L, Schroeder, Steven G, Rosen, Benjamin D, Yang, Liguo, Van Tassell, Curtis P, Liu, George E
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928411/
https://ncbi.nlm.nih.gov/pubmed/29635292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gigascience/giy039
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