Comparative whole genome DNA methylation profiling of cattle sperm and somatic tissues reveals striking hypomethylated patterns in sperm

BACKGROUND: Although sperm DNA methylation has been studied in humans and other species, its status in cattle is largely unknown. RESULTS: Using whole-genome bisulfite sequencing (WGBS), we profiled the DNA methylome of cattle sperm through comparison with three somatic tissues (mammary gland, brain...

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Detalhes bibliográficos
Publicado no:Gigascience
Main Authors: Zhou, Yang, Connor, Erin E, Bickhart, Derek M, Li, Congjun, Baldwin, Ransom L, Schroeder, Steven G, Rosen, Benjamin D, Yang, Liguo, Van Tassell, Curtis P, Liu, George E
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928411/
https://ncbi.nlm.nih.gov/pubmed/29635292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gigascience/giy039
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