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APO010, a synthetic hexameric CD95 ligand, induces human glioma cell death in vitro and in vivo

Death receptor targeting has emerged as one of the promising novel approaches of cancer therapy. The activation of one such prototypic death receptor, CD95 (Fas/APO-1), has remained controversial because CD95 agonistic molecules have exhibited either too strong toxicity or too little activity. The n...

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Detalhes bibliográficos
Main Authors: Eisele, Günter, Roth, Patrick, Hasenbach, Kathy, Aulwurm, Steffen, Wolpert, Fabian, Tabatabai, Ghazaleh, Wick, Wolfgang, Weller, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064626/
https://ncbi.nlm.nih.gov/pubmed/21183510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq176
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