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Cilengitide modulates attachment and viability of human glioma cells, but not sensitivity to irradiation or temozolomide in vitro
Cilengitide is a cyclic peptide antagonist of integrins αvβ3 and αvβ5 that is currently being evaluated as a novel therapeutic agent for recurrent and newly diagnosed glioblastoma. Its mode of action is thought to be mainly antiangiogenic but may include direct effects on tumor cells, notably on att...
Tallennettuna:
| Päätekijät: | , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Duke University Press
2009
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2802395/ https://ncbi.nlm.nih.gov/pubmed/19221171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2009-012 |
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