Prominent Bone Loss Mediated by RANKL and IL-17 Produced by CD4+ T Cells in TallyHo/JngJ Mice

Increasing evidence that decreased bone density and increased rates of bone fracture are associated with abnormal metabolic states such as hyperglycemia and insulin resistance indicates that diabetes is a risk factor for osteoporosis. In this study, we observed that TallyHo/JngJ (TH) mice, a polygen...

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Hauptverfasser: Won, Hee Yeon, Lee, Jin-Ah, Park, Zong Sik, Song, Jin Sook, Kim, Hee Yun, Jang, Su-Min, Yoo, Sung-Eun, Rhee, Youmi, Hwang, Eun Sook, Bae, Myung Ae
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064589/
https://ncbi.nlm.nih.gov/pubmed/21464945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018168
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