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Early-Onset Type 2 Diabetes Impairs Skeletal Acquisition in the Male TALLYHO/JngJ Mouse

Type 2 diabetes (T2D) incidence in adolescents is rising and may interfere with peak bone mass acquisition. We tested the effects of early-onset T2D on bone mass, microarchitecture, and strength in the TALLYHO/JngJ mouse, which develops T2D by 8 weeks of age. We assessed metabolism and skeletal acqu...

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Dettagli Bibliografici
Autori principali: Devlin, M. J., Van Vliet, M., Motyl, K., Karim, L., Brooks, D. J., Louis, L., Conlon, C., Rosen, C. J., Bouxsein, M. L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164927/
https://ncbi.nlm.nih.gov/pubmed/25051433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1041
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