Metabolic Syndrome and Salt-Sensitive Hypertension in Polygenic Obese TALLYHO/JngJ Mice: Role of Na/K-ATPase Signaling

We have demonstrated that Na/K-ATPase acts as a receptor for reactive oxygen species (ROS), regulating renal Na(+) handling and blood pressure. TALLYHO/JngJ (TH) mice are believed to mimic the state of obesity in humans with a polygenic background of type 2 diabetes. This present work is to investig...

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Опубликовано в: :Int J Mol Sci
Главные авторы: Yan, Yanling, Wang, Jiayan, Chaudhry, Muhammad A., Nie, Ying, Sun, Shuyan, Carmon, Jazmin, Shah, Preeya T., Bai, Fang, Pratt, Rebecca, Brickman, Cameron, Sodhi, Komal, Kim, Jung Han, Pierre, Sandrine, Malhotra, Deepak, Rankin, Gary O., Xie, Zi-jian, Shapiro, Joseph I., Liu, Jiang
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6678942/
https://ncbi.nlm.nih.gov/pubmed/31315267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20143495
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