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Metabolic Syndrome and Salt-Sensitive Hypertension in Polygenic Obese TALLYHO/JngJ Mice: Role of Na/K-ATPase Signaling

We have demonstrated that Na/K-ATPase acts as a receptor for reactive oxygen species (ROS), regulating renal Na(+) handling and blood pressure. TALLYHO/JngJ (TH) mice are believed to mimic the state of obesity in humans with a polygenic background of type 2 diabetes. This present work is to investig...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Yan, Yanling, Wang, Jiayan, Chaudhry, Muhammad A., Nie, Ying, Sun, Shuyan, Carmon, Jazmin, Shah, Preeya T., Bai, Fang, Pratt, Rebecca, Brickman, Cameron, Sodhi, Komal, Kim, Jung Han, Pierre, Sandrine, Malhotra, Deepak, Rankin, Gary O., Xie, Zi-jian, Shapiro, Joseph I., Liu, Jiang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6678942/
https://ncbi.nlm.nih.gov/pubmed/31315267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20143495
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