Metabolic Syndrome and Salt-Sensitive Hypertension in Polygenic Obese TALLYHO/JngJ Mice: Role of Na/K-ATPase Signaling

We have demonstrated that Na/K-ATPase acts as a receptor for reactive oxygen species (ROS), regulating renal Na(+) handling and blood pressure. TALLYHO/JngJ (TH) mice are believed to mimic the state of obesity in humans with a polygenic background of type 2 diabetes. This present work is to investig...

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發表在:Int J Mol Sci
Main Authors: Yan, Yanling, Wang, Jiayan, Chaudhry, Muhammad A., Nie, Ying, Sun, Shuyan, Carmon, Jazmin, Shah, Preeya T., Bai, Fang, Pratt, Rebecca, Brickman, Cameron, Sodhi, Komal, Kim, Jung Han, Pierre, Sandrine, Malhotra, Deepak, Rankin, Gary O., Xie, Zi-jian, Shapiro, Joseph I., Liu, Jiang
格式: Artigo
語言:Inglês
出版: MDPI 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6678942/
https://ncbi.nlm.nih.gov/pubmed/31315267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20143495
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