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Inhibition and Genetic Ablation of the B7/CD28 T cell Costimulation Axis Prevents Experimental Hypertension

BACKGROUND: The pathogenesis of hypertension remains poorly understood and treatment is often unsuccessful. Recent evidence suggests that the adaptive immune response plays an important role in this disease. Various hypertensive stimuli cause T cell activation and infiltration into target organs suc...

詳細記述

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書誌詳細
主要な著者: Vinh, Antony, Chen, Wei, Blinder, Yelena, Weiss, Daiana, Robert Taylor, W., Goronzy, Jorg, Weyand, Cornelia, Harrison, David G., Guzik, Tomasz J.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064430/
https://ncbi.nlm.nih.gov/pubmed/21126972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.109.930446
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