Role of the T cell in the genesis of angiotensin II–induced hypertension and vascular dysfunction

Hypertension promotes atherosclerosis and is a major source of morbidity and mortality. We show that mice lacking T and B cells (RAG-1(−/−) mice) have blunted hypertension and do not develop abnormalities of vascular function during angiotensin II infusion or desoxycorticosterone acetate (DOCA)–salt...

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Detalhes bibliográficos
Main Authors: Guzik, Tomasz J., Hoch, Nyssa E., Brown, Kathryn A., McCann, Louise A., Rahman, Ayaz, Dikalov, Sergey, Goronzy, Jorg, Weyand, Cornelia, Harrison, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118469/
https://ncbi.nlm.nih.gov/pubmed/17875676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070657
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