Scavenger receptor CD36 is essential for the cerebrovascular oxidative stress and neurovascular dysfunction induced by amyloid-β

Increasing evidence indicates that cerebrovascular dysfunction plays a pathogenic role in Alzheimer's dementia (AD). Amyloid-β (Aβ), a peptide central to the pathogenesis of AD, has profound vascular effects mediated, for the most part, by reactive oxygen species produced by the enzyme NADPH ox...

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Autors principals: Park, Laibaik, Wang, Gang, Zhou, Ping, Zhou, Joan, Pitstick, Rose, Previti, Mary Lou, Younkin, Linda, Younkin, Steven G., Van Nostrand, William E., Cho, Sunghee, Anrather, Josef, Carlson, George A., Iadecola, Costantino
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2011
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064396/
https://ncbi.nlm.nih.gov/pubmed/21383152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015413108
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