NADPH Oxidase-Derived Reactive Oxygen Species Mediate the Cerebrovascular Dysfunction Induced by the Amyloid β Peptide

Overproduction of the amyloid β (Aβ) peptide is a key factor in the pathogenesis of Alzheimer's disease (AD), but the mechanisms of its pathogenic effects have not been defined. Patients with AD have cerebrovascular alterations attributable to the deleterious effects of Aβ on cerebral blood ves...

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Detalles Bibliográficos
Publicado en:J Neurosci
Autores principales: Park, Laibaik, Anrather, Josef, Zhou, Ping, Frys, Kelly, Pitstick, Rose, Younkin, Steven, Carlson, George A., Iadecola, Costantino
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2005
Materias:
Neurobiology of Disease
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725936/
https://ncbi.nlm.nih.gov/pubmed/15716413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5207-04.2005
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