Analgesia mediated by soluble epoxide hydrolase inhibitors is dependent on cAMP

Pain is a major health concern even though numerous analgesic agents are available. Side effects and lack of wide-spectrum efficacy of current drugs justify efforts to better understand pain mechanisms. Stabilization of natural epoxy-fatty acids (EFAs) through inhibition of the soluble epoxide hydro...

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Bibliografiske detaljer
Main Authors: Inceoglu, Bora, Wagner, Karen, Schebb, Nils H., Morisseau, Christophe, Jinks, Steven L., Ulu, Arzu, Hegedus, Christine, Rose, Tristan, Brosnan, Robert, Hammock, Bruce D.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064364/
https://ncbi.nlm.nih.gov/pubmed/21383170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101073108
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