RUNX3 Maintains the Mesenchymal Phenotype after Termination of the Notch Signal

Notch is a critical mediator of endothelial-to-mesenchymal transition (EndMT) during cardiac cushion development. Slug, a transcriptional repressor that is a Notch target, is an important Notch effector of EndMT in the cardiac cushion. Here, we report that the runt-related transcription factor RUNX3...

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Autors principals: Fu, YangXin, Chang, Alex Chia Yu, Fournier, Michèle, Chang, Linda, Niessen, Kyle, Karsan, Aly
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064231/
https://ncbi.nlm.nih.gov/pubmed/21288908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.222331
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