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Co-ordinating Notch, BMP, and TGF-β signaling during heart valve development

Congenital heart defects affect approximately 1–5 % of human newborns each year, and of these cardiac defects 20–30 % are due to heart valve abnormalities. Recent literature indicates that the key factors and pathways that regulate valve development are also implicated in congenital heart defects an...

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Detalhes bibliográficos
Publicado no:Cell Mol Life Sci
Main Authors: Garside, Victoria C., Chang, Alex C., Karsan, Aly, Hoodless, Pamela A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Basel 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996658/
https://ncbi.nlm.nih.gov/pubmed/23161060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-012-1197-9
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