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Role of Insert-1 of Myosin VI in Modulating Nucleotide Affinity

Myosin VI is unique in its directionality among myosin superfamily members and also displays a slow and strain-dependent rate of ATP binding that allows for gating between its heads. In this study we demonstrate that leucine 310 is positioned by a class VI-specific insert, insert-1, so as to account...

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Detalhes bibliográficos
Main Authors: Pylypenko, Olena, Song, Lin, Squires, Gaelle, Liu, Xiaoyan, Zong, Alan B., Houdusse, Anne, Sweeney, H. Lee
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064223/
https://ncbi.nlm.nih.gov/pubmed/21278381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.200626
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