Osteopontin Undergoes Polymerization in Vivo and Gains Chemotactic Activity for Neutrophils Mediated by Integrin α9β1

Osteopontin (OPN) is an integrin-binding inflammatory cytokine that undergoes polymerization catalyzed by transglutaminase 2. We have previously reported that polymeric OPN (polyOPN), but not unpolymerized OPN (OPN*), attracts neutrophils in vitro by presenting an acquired binding site for integrin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Nishimichi(西, Norihisa, 道教尚), Hayashita-Kinoh(早, Hiromi, 下- 喜納裕美), Chen, Chun, Matsuda(松, Haruo, 田治男), Sheppard, Dean, Yokosaki(横, Yasuyuki, 崎恭之)
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2011
Pynciau:
Glycobiology and Extracellular Matrices
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064171/
https://ncbi.nlm.nih.gov/pubmed/21321126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.189258
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg