Chronic Inhibition of Pyruvate Dehydrogenase in Heart Triggers an Adaptive Metabolic Response

Diabetic cardiac dysfunction is associated with decreased rates of myocardial glucose oxidation (GO) and increased fatty acid oxidation (FAO), a fuel shift that has been shown to sensitize the heart to ischemic insult and ventricular dysfunction. We sought to evaluate the metabolic and functional co...

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Detaylı Bibliyografya
Asıl Yazarlar: Chambers, Kari T., Leone, Teresa C., Sambandam, Nandakumar, Kovacs, Attila, Wagg, Cory S., Lopaschuk, Gary D., Finck, Brian N., Kelly, Daniel P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2011
Konular:
Metabolism
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064169/
https://ncbi.nlm.nih.gov/pubmed/21321124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.217349
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