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ACVR1B (ALK4, activin receptor type 1B) gene mutations in pancreatic carcinoma

DPC4 is known to mediate signals initiated by type β transforming growth factor (TGFβ) as well as by other TGFβ superfamily ligands such as activin and BMP (bone morphogenic proteins), but mutational surveys of such non-TGFβ receptors have been negative to date. Here we describe the gene structure a...

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Autori principali: Su, Gloria H., Bansal, Ravi, Murphy, Kathleen M., Montgomery, Elizabeth, Yeo, Charles J., Hruban, Ralph H., Kern, Scott E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC30640/
https://ncbi.nlm.nih.gov/pubmed/11248065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051484398
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