A Bayesian population PBPK model for multiroute chloroform exposure

A Bayesian hierarchical model was developed to estimate the parameters in a physiologically based pharmacokinetic (PBPK) model for chloroform using prior information and biomarker data from different exposure pathways. In particular, the model provides a quantitative description of the changes in ph...

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Bibliographic Details
Main Authors:	Yang, Yuching, Xu, Xu, Georgopoulos, Panos G.
Format:	Artigo
Language:	Inglês
Published:	2009
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3063650/ https://ncbi.nlm.nih.gov/pubmed/19471319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jes.2009.29
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A Bayesian population PBPK model for multiroute chloroform exposure

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