Bayesian Analysis of a Lipid-Based Physiologically Based Toxicokinetic Model for a Mixture of PCBs in Rats

A lipid-based physiologically based toxicokinetic (PBTK) model has been developed for a mixture of six polychlorinated biphenyls (PCBs) in rats. The aim of this study was to apply population Bayesian analysis to a lipid PBTK model, while incorporating an internal exposure-response model linking enzy...

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Autors principals: Sasso, Alan F., Georgopoulos, Panos G., Isukapalli, Sastry S., Krishnan, Kannan
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270437/
https://ncbi.nlm.nih.gov/pubmed/22315591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/895391
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