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A Bayesian population PBPK model for multiroute chloroform exposure
A Bayesian hierarchical model was developed to estimate the parameters in a physiologically based pharmacokinetic (PBPK) model for chloroform using prior information and biomarker data from different exposure pathways. In particular, the model provides a quantitative description of the changes in ph...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3063650/ https://ncbi.nlm.nih.gov/pubmed/19471319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jes.2009.29 |
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