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Predicting crossover generation in DNA shuffling
We introduce a quantitative framework for assessing the generation of crossovers in DNA shuffling experiments. The approach uses free energy calculations and complete sequence information to model the annealing process. Statistics obtained for the annealing events then are combined with a reassembly...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The National Academy of Sciences
2001
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC30635/ https://ncbi.nlm.nih.gov/pubmed/11248060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051631498 |
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