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Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins

The understanding of integral membrane protein (IMP) structure and function is hampered by the difficulty of handling these proteins. Aqueous solubilization, necessary for many types of biophysical analysis, generally requires a detergent to shield the large lipophilic surfaces displayed by native I...

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Detaylı Bibliyografya
Asıl Yazarlar: Chae, Pil Seok, Rasmussen, Søren G. F., Rana, Rohini, Gotfryd, Kamil, Chandra, Richa, Goren, Michael A., Kruse, Andrew C., Nurva, Shailika, Loland, Claus J., Pierre, Yves, Drew, David, Popot, Jean-Luc, Picot, Daniel, Fox, Brian G., Guan, Lan, Gether, Ulrik, Byrne, Bernadette, Kobilka, Brian, Gellman, Samuel H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063152/
https://ncbi.nlm.nih.gov/pubmed/21037590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1526
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